Exit Exam Pharmaceutical Chemistry Syllabus

Chapter 1: (A) Introduction to Pharmaceutical chemistry

  • Scope and Objective of Pharmaceutical Chemistry

Chapter 1: (B) Sources and types of errors

  • Accuracy
  • Precision
  • Significant Figures

Chapter 1: (C) Impurities in Pharmaceuticals

  • Source of impurities in Pharmacopoeial substances
  • effect of impurities in Pharmacopoeial substances
  • Importance of Limit Test
  • Procedures and Principle of Limit tests for Chlorides
  • Limit tests for Sulphates
  • Principle and Procedures of Limit tests for Iron
  • Principle and Procedures of Limit tests for Heavy Metals and Arsenic

Chapter 2: (A) Volumetric Analysis

  • Fundamentals of Volumetric Analysis
  • Acid-Base Titration
  • Non-Aqueous Titration
  • Precipitation Titration
  • Complexometric Titration
  • Redox Titration

Chapter 2: (B) Gravimetric Analysis

  • Principle and Method of Gravimetry Analysis

Chapter 3: (A) Haematinics

  • Market Preparations, Pharmaceutical formulations, use and storage conditions of Ferrous sulphate, Ferrous ascorbate, Ferrous fumarate, Carbonyl iron and Ferric ammonium citrate.

Chapter 3: (B) Gastrointestinal Agents

  • Market Preparations, Pharmaceutical formulations, use and storage conditions of Antacids: Magnesium hydroxide, Aluminium hydroxide gel, Calcium Carbonate, Adsorbents, Cathartics, Aluminium hydroxide gel, Magaldrate, Adsorbents, Sodium bicarbonate

Chapter 3: (C) Topical agents

  • Market Preparations, Pharmaceutical formulations, use and storage conditions of Ionic Silver, Hydrogen peroxide, Boric acid, Potassium permanganate, Silver Nitrate, Chlorhexidine Gluconate.

Chapter 3: (D) Dental products

  • Market Preparations, Pharmaceutical formulations, use and storage conditions of Sodium fluoride, Denture adhesives, Calcium carbonate, Denture cleaners, Mouthwashes

Chapter 3: (E) Medicinal Gases

  • Market Preparations, Pharmaceutical formulations, use and storage conditions of nitrous oxide, Carbon dioxide, oxygen.

Chapter 4: Nomenclature of Organic Systems

Chapter 5: Drugs Acting on Central Nervous System

  • Anaesthetics: Ketamine Hydrochloride, Thiopental Sodium, Propofol
  • Sedatives and Hypnotics: Alprazolam, Phenobarbital, Diazepam, Nitrazepam
  • Antipsychotics: Haloperidol, Sulpiride, Quetiapine, Chlorpromazine Hydrochloride, Risperidone, Olanzapine, Lurasidone
  • Anticonvulsants: Carbamazepine, Valproic Acid, Topiramate, Lamotrigine, Phenytoin, Clonazepam, Gabapentin, Vigabatrin
  • Anti-Depressants: Imipramine Hydrochloride, Venlafaxine, Sertraline, Escitalopram, Paroxetine, Amitriptyline Hydrochloride, Fluoxetine, Duloxetine, Citalopram, Fluvoxamine

Chapter 6: Drugs Acting on Autonomic Nervous System

  • Sympathomimetic Agents:
    • Direct Acting: Epinephrine, Dopamine, Salbutamol, Tetrahydrozoline, Nor-Epinephrine, Phenylephrine, Terbutaline, Naphazoline.
    • Indirect Acting Agents: Pseudoephedrine, Hydroxy Amphetamine
    • Agents With Mixed Mechanism: Metaraminol, Ephedrine
  • Adrenergic Antagonists:
    • Alpha Adrenergic Blockers: Phentolamine, Tolazoline, Prazosin, Phenoxybenzamine
    • Beta-Adrenergic Blockers: Atenolol, Propranolol, Carvedilol
  • Cholinergic Drugs and Related Agents:
    • Direct Acting Agents: Carbachol, Acetylcholine, Pilocarpine
    • Cholinesterase Inhibitors: Edrophonium Chloride, Pralidoxime Chloride, Neostigmine, Echothiopate Iodide, Pralidoxime Chloride, Tacrine Hydrochloride
  • Cholinergic Blocking Agents: Ipratropium Bromide, Atropine Sulphate
  • Synthetic Cholinergic Blocking Agents: Cyclopentolate Hydrochloride, Dicyclomine Hydrochloride, Tropicamide, Clidinium Bromide

Chapter 7: Drugs Acting on Cardiovascular System

  • Anti-Arrhythmic Drugs: Procainamide Hydrochloride, Phenytoin Sodium, Lorcainide Hydrochloride, Sotalol, Quinidine Sulphate, Verapamil, Lidocaine Hydrochloride, Amiodarone
  • Anti-Hypertensive Agents: Captopril, Methyldopate Hydrochloride, Hydralazine Hydrochloride, Propranolol, Ramipril, Clonidine Hydrochloride, Nifedipine
  • Antianginal Agents: Isosorbide Dinitrate

Chapter 8: Diuretics

  • Frusemide, Chlorthalidone, Metolazone, Spironolactone, Acetazolamide, Bumetanide, Benzthiazide, Xipamide

Chapter 9: Hypoglycemic Agents

  • Metformin, Glimepiride, Repaglinide, Gliptins, Insulin and Its Preparations, Glibenclamide, Pioglitazone, Gliflozins.

Chapter 10: Analgesic And Anti-Inflammatory Agents

  • Narcotic Antagonists, Morphine Analogues
  • Nonsteroidal Anti Inflammatory Agents (NSAIDs): Diclofenac, Piroxicam, Mefenamic Acid, Aceclofenac, Aspirin, Ibuprofen, Celecoxib, Paracetamol

Chapter 11: Anti-Infective Agents

  • Antifungal Agents: Griseofulvin, Ketoconazole, Fluconazole, Amphotericin-B, Miconazole, Itraconazole, Naftifine Hydrochloride
  • Urinary Tract Anti-Infective Agents: Ciprofloxacin, Moxifloxacin, Norfloxacin, Ofloxacin
  • Anti-Tubercular Agents: Ethambutol, Pyrazinamide, Bedaquiline, Pretomanid, INH, Para Amino Salicylic Acid, Rifampicin, Delamanid
  • Antiviral Agents: Idoxuridine, Foscarnet, Ribavirin, Favipiravir, Amantadine Hydrochloride, Acyclovir, Zidovudine, Remdesivir
  • Antimalarials: Chloroquine Phosphate, Mefloquine, Pyrimethamine, Quinine Sulphate, Primaquine Phosphate, Cycloguanil
  • Sulfonamides: Sulfadiazine, Sulfacetamide, Cotrimoxazole, Sulfanilamide, Sulfamethoxazole, Mafenide Acetate, Dapsone

Chapter 12: Antibiotics

  • Amoxicillin, Streptomycin, Penicillin G, Cloxacillin
  • Tetracyclines: Minocycline, Doxycycline
  • Macrolides: Azithromycin, Erythromycin
  • Miscellaneous: Clindamycin, Chloramphenicol

Chapter 13: Anti Neoplastic Agents

  • Busulfan, Fluorouracil, Dactinomycin, Vinblastine Sulphate, Dromostanolone Propionate, Cyclophosphamide, Mercaptopurine, Methotrexate, Doxorubicin Hydrochloride, Cisplatin