BP503. T. PHARMACOLOGY-II (Theory)

UNIT-I  Pharmacology of drugs acting on cardiovascular system

  1. Introduction to hemodynamic and electrophysiology of heart.
  2. Drugs used in congestive heart failure.
  3. Anti-hypertensive drugs.
  4. Anti-anginal drugs.
  5. Anti-arrhythmic drugs.
  6. Anti-hyperlipidemic drugs.

UNIT-II 

  1. Pharmacology of drugs acting on cardio vascular system
  2. Drug used in the therapy of shock.
  3. Hematinics, coagulants and anticoagulants.
  4. Fibrinolytics and anti-platelet drugs.
  5. Plasma volume expanders

2.  Pharmacology of drugs acting on urinary system

  1. Diuretics
  2. Anti-diuretics.

UNIT-III        

  • Autocoids and related drugs
    • Introduction to autacoids and classification
    • Histamine, 5-HT and their antagonists.
    • Prostaglandins, Thromboxanes and Leukotrienes.
    • Angiotensin, Bradykinin and Substance P.
    • Non-steroidal anti-inflammatory agents
    • Anti-gout drugs
    • Antirheumatic drugs

UNIT-IV     

  • Pharmacology of drugs acting on endocrine system
    • Basic concepts in endocrine pharmacology.
    • Anterior Pituitary hormones- analogues and their inhibitors.
    • Thyroid hormones- analogues and their inhibitors.
    • Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin-D.
    • Insulin, Oral Hypoglycemic agents and glucagon.
    • ACTH and corticosteroids.

UNIT-V       

  • Pharmacology of drugs acting on endocrine system
    • Androgens and Anabolic steroids.
    • Estrogens, progesterone and oral contraceptives.
    • Drugs acting on the uterus.

6.  Bioassay

  1. Principles and applications of bioassay.
  2. Types of bioassay.
  3. Bioassay of insulin, oxytocin, vasopressin, ACTH.
  4. tubocurarine, digitalis, histamine and 5-HT.