BP103T. PHARMACEUTICS- I (Theory)

UNIT – I                                                                                                        

  • Historical background and development of profession of pharmacy: History of profession of Pharmacy in India in relation to pharmacy education, industry and organization.
  • Pharmacy as a career.
  • Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.
  • Dosage forms: Introduction to dosage forms, classification and definitions.
  • Prescription: Definition, Parts of prescription, handling of Prescription and Errors in prescription.
  • Posology: Definition, Factors affecting posology. Pediatric dose calculations based on age, body weight and body surface area.

UNIT – II                                                         

  • Pharmaceutical calculations: Weights and measures – Imperial & Metric system, Calculations involving percentage solutions, alligation, proof spirit and isotonic solutions based on freezing point and molecular weight.
  • Powders: Definition, classification, advantages and disadvantages,Simple & compound powders – official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.
  • Liquid dosage forms: Advantages and disadvantages of liquid dosage forms. Excipients used in formulation of liquid dosage forms. Solubility enhancement techniques

UNIT – III                                                         

  • Monophasic liquids: Definitions and preparations of the following: 1. Gargles 2. Mouthwashes 3. Throat Paint 4. Eardrops 5. Nasal drops 6. Enemas 7. Syrups 8. Elixirs 9. Liniments 10. Lotions.

·    Biphasic liquids:

  • Suspensions: Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and Deflocculated suspension & stability problems and methods to overcome.
  • Emulsions: Definition, classification, emulsifying agent, test for the identification of type ofEmulsion, Methods of preparation & stability problems and methods to overcome.

UNIT – IV                                                     

  • Suppositories: Definition, types, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories.
  • Pharmaceutical incompatibilities: Definition, classification, physical, chemical and therapeutic incompatibilities with examples.

UNIV – V                                      

  • Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms